D-chiro-inositol transport protein
function
D-chiro-inositol uptake
product
D-chiro-inositol transport protein
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.3|Carbohydrate transporter][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.16|Utilization of inositol][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|IolR regulon]Gene
Coordinates on the chromosome (coding sequence)
4,076,842 -> 4,078,158
The protein
Catalyzed reaction/ biological activity
uptake of D-chiro-inositol [Pubmed|20530884][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|iolA]-[protein|search|iolB]-[protein|search|iolC]-[protein|search|iolD]-[protein|search|iolE]-[protein|search|iolF]-[protein|search|iolG]-[protein|search|iolH]-[protein|search|iolI]-[protein|search|iolJ]'' [Pubmed|9226270][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9226270]Regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]induced by inositol ([protein|search|IolR]) [Pubmed|9887260,9226270]Regulatory mechanism
[protein|search|IolR]: transcription repression [Pubmed|9887260,9226270][protein|search|CcpA]: transcription repression [Pubmed|10666464]Labs working on this gene/protein
[SW|Yasutaro Fujita], University of Fukuyama, Japan[[Ken-ichi Yoshida]], Kobe University, JapanReferences
9226270,11807058,9887260,18310071,20530884 
