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amj [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
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amj [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

lipid II flippase, alternative to MurJ
locus
BSU04230
pI
10.00
mw
29.00 kDa
function
export of lipid II
product
lipid II flippase
essential
no
synonyms
ydaH

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigM regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    474,731 -> 475,540

    Phenotypes of a mutant

  • an ''[protein|search|amj] [protein|search|murJ]'' double mutant is not viable [Pubmed|25918422]
  • The protein

    [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''amj'' [Pubmed|17434969]
  • [SW|Sigma factor]

  • [protein|search|SigM] [Pubmed|17434969]
  • Regulation

  • induced in the stationary phase due to the internal production of toxic peptides ([SW|SdpC], [SW|SkfA]) [Pubmed|26364265]
  • References

    Reviews

  • 26679002
  • Original Publications

  • 17434969,25918422,17434969,26364265