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sndA [Mon Aug 31 2015 13:56:13 GMT+0200 (CEST)]
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sndA [Mon Aug 31 2015 13:56:13 GMT+0200 (CEST)]

sulphur compound N-deacetylase, required for the conversion of S-methyl-cysteine to cysteine
locus
BSU29290
pI
5.55
mw
45.00 kDa
function
utilization of S-methyl-cysteine
product
sulphur compound N-deacetylase
essential
no
synonyms
hipO, ytnL

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.1|Conversion of S-methyl cysteine to cysteine]
  • [category|SW 6|Groups of genes] → [category|SW 6.11|Efp-dependent proteins]
  • syns
    hipO, ytnL

    [SW|Categories] containing this gene/protein

  • [SW|sulfur metabolism]
  • This gene is a member of the following [SW|regulons]

  • [SW|CymR regulon], [SW|AscR regulon], [SW|Efp-dependent proteins]
  • Gene

    Phenotypes of a mutant

  • a ''[protein|search|sndA] [protein|search|sndB] [protein|search|sndC]'' triple mutant does not grow with N-acetyl cysteine [Pubmed|23944997]
  • The protein

    Protein family

  • peptidase M20 family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|SndB], [protein|search|SndC], [protein|search|DapI]
  • Expression and Regulation

    Operon

  • ''[protein|search|snaA]-[protein|search|tcyJ]-[protein|search|tcyK]-[protein|search|tcyL]-[protein|search|tcyM]-[protein|search|tcyN]-[protein|search|cmoO]-[protein|search|cmoI]-[protein|search|cmoJ]-[protein|search|ribR]-[protein|search|sndA]-[protein|search|ytnM]'' [Pubmed|15668000]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|15272571]
  • Regulation

  • repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16109943]
  • induced in the presence of S-methyl-cysteine ([protein|search|AscR]) [Pubmed|23944997]
  • Regulatory mechanism

  • [protein|search|CymR]: transcription repression [Pubmed|16109943]
  • [protein|search|AscR]: transcription activation [Pubmed|16109943]
  • References

  • 16109943,15668000,15272571,23944997