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gerR
probably DNA-binding protein, regulates transcription of some spore coat genes
function
spore coat formation and resistance of spores to lysozyme
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.8|Not yet assigned][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]Gene
Coordinates
1,576,129 1,576,710
The protein
[SW|Domains]
HTH myb-type domain (aa 1-61) (according to UniProt)Modification
phosphorylated on Ser-180 [Pubmed|20509597]Expression and Regulation
Operons
genes
[gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]
description
[pubmed|22383849]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: activation, [Pubmed|20435725], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]regulation
expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE], [SW|SpoIIID]) [Pubmed|15699190,20435725]view in new tabBiological materials
Mutant
MGNA-B252 (ylbO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1251 NBRP B. subtilis, Japan]BKE15090 ([gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE15090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATTCAATCTCCCTCCAT, downstream forward: _UP4_TAAAGAAACGCCTGAAATGABKK15090 ([gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK15090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATTCAATCTCCCTCCAT, downstream forward: _UP4_TAAAGAAACGCCTGAAATGAReferences
Reviews
Original Publications
15383836,15621419,20435725,12850135,12107147,20509597