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pstBB [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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pstBB [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

phosphate ABC transporter (ATP-binding protein)
locus
BSU24950
pI
7.77
mw
29.00 kDa
function
high-affinity phosphate uptake
product
phosphate ABC transporter (ATP-binding protein)
essential
no
ec
3.6.3.27
synonyms
pstB, yqgK, yzmF

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.6|Uptake of ions]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|phosphate metabolism]
  • This gene is a member of the following [SW|regulons]

  • [SW|PhoP regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,577,210 -> 2,577,992

    The protein

    Catalyzed reaction/ biological activity

  • ATP + H2O + phosphate(Out) = ADP + phosphate + phosphate(In) (according to Swiss-Prot)
  • [SW|Interactions]

  • ([SW|PstBA]-[SW|PstBB])-([protein|search|PstA]-[protein|search|PstC])-[protein|search|PstS] [Pubmed|10092453]
  • Expression and Regulation

    Operon

  • ''[protein|search|pstS]-[protein|search|pstC]-[protein|search|pstA]-[SW|pstBA]-[SW|pstBB]'' [Pubmed|9098050]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9098050]
  • Regulation

  • expressed under conditions of phosphate limitation (5000-fold induced) ([protein|search|PhoP]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]
  • Regulatory mechanism

  • [protein|search|PhoP]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]
  • Additional information

  • mRNA processing between '[protein|search|pstS]' and '[protein|search|pstC]' to maintain higher concentrations of [protein|search|PstS] relative to other components of the [[ABC transporter]] [PubMed|15289558]
  • Labs working on this gene/protein

  • [SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]
  • References

  • 9098050,12897025,10913081,10092453,15289558,9098050,9593301