membrane protein, part of the type VII protein secretion system YukD-YukC-YukB-YueB-YueC, receptor for phage SPPI
product
part of the type VII protein secretion system, receptor for phage SPPI
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.6|Phage-related functions][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|phage-related functions], [SW|protein secretion], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|DegU regulon]Gene
Coordinates on the chromosome (coding sequence)
3,266,687 -> 3,269,917
Phenotypes of a mutant
resistance to phage SPPI [Pubmed|15576783]loss of secretion of [protein|search|YukE] [Pubmed|24798022]The protein
Catalyzed reaction/ biological activity
receptor for phage SPP1 [Pubmed|15576783]required for depolarization of the cytoplasmic membrane upon binding of phage SPP1 [Pubmed|22154073][SW|Localization]
cell membrane [Pubmed|15576783,23861817], localizes preferentially to the cell poles [Pubmed|21705600]exposed to the surface [Pubmed|16481324]cytoplasm (homogeneous) [Pubmed|16479537][SW|Interactions]
[protein|search|YueB] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [SW|interactions] [Pubmed|21630458]Expression and Regulation
Operon
''[protein|search|yukE]-[protein|search|yukD]-[protein|search|yukC]-[protein|search|yukB]-[protein|search|yueB]-[protein|search|yueC]'' [Pubmed|22383849,15576783][SW|Sigma factor]
[protein|search|SigA] [Pubmed|22383849]Regulation
not expressed in the lab strain 168, due to lack of [protein|search|DegU]-P [Pubmed|23861817]expressed in the stationary phase [Pubmed|23861817]Regulatory mechanism
[protein|search|DegU]-P: transcription activation [Pubmed|23861817]References
Reviews
Original publications
16479537,16481324,15576783,21630458,18487323,17611601,22383849,22171743,21705600,22154073,23861817,24798022,27179995 
