4.5 S RNA, causes RNA-driven elongation arrest by interaction with the 23S rRNA
function
presecretory protein translocation
product
small cytoplasmic RNA (scRNA, 4.5S RNA)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.3|Small cytoplasmatic RNA][SW|Categories] containing this gene/protein
[SW|protein secretion], [SW|essential genes], [SW|ncRNA], [SW|household RNA]Gene
Coordinates on the chromosome (coding sequence)
26,533 -> 26,635
Phenotypes of a mutant
the gene is essential [Pubmed|7506707]The protein
Catalyzed reaction/ biological activity
=== Extended information on the RNA===Structure
[PDB|4UE4] (complex [protein|search|Ffh]-[protein|search|Scr] RNA) [Pubmed|26344568][SW|Interactions]
[protein|search|Scr]-[protein|search|Ffh] in the [SW|signal recognition particle] [Pubmed|26344568][protein|search|Scr]-[[23S rRNA]] [Pubmed|26344568]Expression and Regulation
Operon
''[protein|search|yaaJ]-[protein|search|scr], [protein|search|scr][SW|Sigma factor]
[protein|search|SigA] (both promoters)Labs working on this gene/RNA
[SW|David Bechhofer], Mount Sinai School, New York, USA [http://www.mountsinai.org/Research/Centers Laboratories and Programs/Bechhofer Laboratory?citype=Physician&ciid=Bechhofer David H 1255565 Homepage]References
Reviews
Original publications
9346318,2468993,17576666,1372600,7506707,1383945,7538759,10224127,9677377,8662730,10222262,25270875,25402410,26344568,26883633 
