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ydeL
similar to transcriptional regulator ([SW|MocR/ GabR family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]Gene
Coordinates
571,389 572,780
The protein
Protein family
[SW|MocR/ GabR family ][Pubmed|22020104][SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)[SW|Domains]
N-terminal DNA-binding helix-turn-helix motif; C-terminal domain is homologous to PLP-binding large domain of aminotransferases.[SW|HTH gntR-type domain] (aa 13-81) (according to UniProt)[SW|Cofactors]
PLPStructure
[PDB|4MGR] ([protein|C7C36FAC0CE72226960FC7E8E016B8EC77AF1036|GabR], 38% identity) [pubmed|24127574][SW|Localization]
nucleoid (Homogeneous) [Pubmed|16479537]Biological materials
Mutant
MGNA-C083 (ydeL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2081 NBRP B. subtilis, Japan]BKE05240 ([gene|05A23F4611674B0092262DEC309F7AD6B9B5BE30|ydeL]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCGCGTTGTTCTCCT, downstream forward: _UP4_TGAGGGAGCTTTCAGTTTAGBKK05240 ([gene|05A23F4611674B0092262DEC309F7AD6B9B5BE30|ydeL]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCGCGTTGTTCTCCT, downstream forward: _UP4_TGAGGGAGCTTTCAGTTTAGReferences
11756427,16479537,21630458,22020104,24127574