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ndoAI
antitoxin, antagonist for [protein|2E5A557E417CB355331CC0555D46A79793EB90B3|EndoA]
function
inhibition of [protein|2E5A557E417CB355331CC0555D46A79793EB90B3|EndoA]
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.2|Type 2 TA systems]Gene
Coordinates
518,657 518,938
The protein
Protein family
mazE/ndoAI family (single member, according to UniProt)Structure
[PDB|4ME7] ([protein|2E5A557E417CB355331CC0555D46A79793EB90B3|NdoA]-[protein|052BD59112DBE2F1DAC9DA5A7B0EA8DAF8D6FC47|NdoAI] complex) [Pubmed|24120662]Expression and Regulation
Operons
genes
[gene|052BD59112DBE2F1DAC9DA5A7B0EA8DAF8D6FC47|ndoAI]-[gene|2E5A557E417CB355331CC0555D46A79793EB90B3|ndoA]
description
[Pubmed|15882409]
additional information
An [ncRNA|search|antisense RNA] is predicted for '[protein|search|ndoA]' [PubMed|20525796]view in new tabgenes
[gene|CB0B6C69CB5CFF6FE30C3F95991F309C8DE1E344|alr]-[gene|052BD59112DBE2F1DAC9DA5A7B0EA8DAF8D6FC47|ndoAI]-[gene|2E5A557E417CB355331CC0555D46A79793EB90B3|ndoA]
description
[pubmed|22383849]
Biological materials
Mutant
BKE04650 ([gene|052BD59112DBE2F1DAC9DA5A7B0EA8DAF8D6FC47|ndoAI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE04650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAAAACATACACCTCCAC, downstream forward: _UP4_CGCTTAGTCAGCGGAGGATABKK04650 ([gene|052BD59112DBE2F1DAC9DA5A7B0EA8DAF8D6FC47|ndoAI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK04650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACCCCTTTTTCTCAATTG, downstream forward: _UP4_TAACCGCCAAAGGCCAAACAReferences
17416361,15882409,24120662,23736285 
