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Category: Essential genes
Name | Function |
accA | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
accB | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
accC | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
accD | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
acpA | fatty acid biosynthesis |
acpS | fatty acid biosynthesis |
adk | ADP formation |
alaS | translation |
alr | peptidoglycan biosynthesis |
argS | translation |
aroE | biosynthesis of aromatic amino acids |
aroF | biosynthesis of aromatic amino acids |
aroK | biosynthesis of aromatic amino acids |
asd | biosynthesis of threonine, lysine, dipicolic acid, peptidoglycan |
aspS | translation |
birA | regulation of biotin synthesis, addition of biotin to proteins |
cca | tRNA modification |
cdsA | biosynthesis of phospholipids |
cmk | synthesis of CTP and dCTP |
cysS | translation |
dapA | biosynthesis of lysine and peptidoglycan |
dapB | biosynthesis of lysine and peptidoglycan |
dapF | biosynthesis of lysine and peptidoglycan |
dapG | biosynthesis of lysine and peptidoglycan |
ddl | peptidoglycan precursor biosynthesis |
dfrA | biosynthesis of folate |
divIB | septum formation |
divIC | septum formation |
dnaA | [category|SW 3.1.1|DNA replication] |
dnaB | [category|SW 3.1.1|DNA replication] |
dnaC | [category|SW 3.1.1|DNA replication] |
dnaD | [category|SW 3.1.1|DNA replication] |
dnaE | [category|SW 3.1.1|DNA replication](lagging strand) |
dnaG | [category|SW 3.1.1|DNA replication] |
dnaI | [category|SW 3.1.1|DNA replication] |
dnaN | [category|SW 3.1.1|DNA replication], DNA repair |
dnaX | [category|SW 3.1.1|DNA replication] |
dxs | biosynthesis of thiamine, MEP pathway of isoprenoid biosynthesis |
eno | enzyme in glycolysis/ gluconeogenesis |
era | ribosome assembly |
fabD | fatty acid biosynthesis |
fabF | fatty acid biosynthesis |
fabG | fatty acid biosynthesis |
ffh | presecretory protein translocation |
folB | biosynthesis of folate |
folC | biosynthesis of folate |
folE | biosynthesis of folate and queuosine |
folK | biosynthesis of folate |
frr | translation |
ftsA | formation of Z-ring |
ftsL | septum formation |
ftsW | cell division |
ftsY | protein secretion |
ftsZ | formation of Z-ring |
fusA | translation |
gapA | catabolic enzyme in glycolysis |
gatA | translation |
gatB | translation |
gatC | translation |
gcaD | cell wall metabolism |
glmM | cell wall synthesis |
glmS | cell wall synthesis |
gltX | translation |
glyQ | translation |
glyS | translation |
gmk | GTP biosynthesis |
groEL | protein folding and re-folding |
groES | protein folding and re-folding |
gyrA | DNA supercoiling, control of [category|SW 3.1.1|replication] initiation |
gyrB | DNA supercoiling, control of [category|SW 3.1.1|replication] initiation |
hbs | DNA packaging, regulation of nucleoid compaction |
hisS | translation |
holA | [category|SW 3.1.1|DNA replication] |
holB | [category|SW 3.1.1|DNA replication] |
ileS | translation |
infA | translation |
infB | translation |
infC | translation |
ispC | MEP pathway of isoprenoid biosynthesis |
ispD | MEP pathway of isoprenoid biosynthesis |
ispE | MEP pathway of isoprenoid biosynthesis |
ispF | MEP pathway of isoprenoid biosynthesis |
ispG | MEP pathway of isoprenoid biosynthesis |
ispH | MEP pathway of isoprenoid biosynthesis |
leuS | translation |
ligA | replication |
lysS | translation |
mbl | [SW|cell shape] determination |
menA | biosynthesis of menaquinone |
menB | biosynthesis of menaquinone |
menC | biosynthesis of menaquinone |
menD | biosynthesis of menaquinone |
menE | biosynthesis of menaquinone |
metK | S-adenosylmethionine synthesis |
metS | translation |
mgtE | magnesium uptake |
mnaA | biosynthesis of teichoic acid |
mraY | peptidoglycan precursor biosynthesis |
mreB | [SW|cell shape] determination |
mreC | [SW|cell shape] determation |
mreD | [SW|cell shape] determation |
mrpA | sodium export |
mrpB | sodium export |
mrpC | sodium export |
mrpD | sodium export |
mrpE | sodium export |
mrpF | sodium export |
mrpG | sodium export |
murAA | peptidoglycan precursor biosynthesis |
murB | peptidoglycan precursor biosynthesis |
murC | peptidoglycan precursor biosynthesis |
murD | peptidoglycan precursor biosynthesis |
murE | peptidoglycan precursor biosynthesis |
murF | peptidoglycan precursor biosynthesis |
murG | peptidoglycan precursor biosynthesis |
nadD | NAD biosynthesis |
nadE | NAD biosynthesis |
nadF | generation of NADP from NAD |
nrdE | synthesis of deoxyribonucleoside triphosphates |
nrdF | synthesis of deoxyribonucleoside triphosphates |
nrdI | synthesis of deoxyribonucleoside triphosphates |
nusA | transcription |
obg | ribosome assembly, may be required to stimulate activity |
parC | chromosome segregation and compaction |
parE | chromosome segregation and compaction |
patA | biosynthesis of lysine and peptidoglycan |
pbpB | septation, [SW|cell division] |
pcrA | coupling of DNA replication, transcription, recombination and segregation |
pgm | enzyme in glycolysis / gluconeogenesis |
pgsA | biosynthesis of phospholipids |
pheS | translation |
pheT | translation |
plsC | biosynthesis of phospholipids |
plsX | biosynthesis of phospholipids |
plsY | biosynthesis of phospholipids |
pncB | NAD salvage |
polC | [category|SW 3.1.1|DNA replication] |
ppaC | recovery of phosphate ions from pyrophosphate |
prfA | translation |
prfB | translation |
priA | [category|SW 3.1.1|DNA replication]initiation |
proS | translation |
prp | maturation of [protein|4626C659D6F1A81CCC94030F1CBAF7FEC3DE19CA|ribosomal protein L27] |
prs | phosphoribosylpyrophosphate synthesis (biosynthesis of histidine) |
prsA | protein folding |
pyrG | pyrimidine biosynthesis |
pyrH | pyrimidine biosynthesis |
racE | peptidoglycan precursor biosynthesis |
rbgA | [category|SW 3.3.1.6|Ribosome assembly] |
ribC | FAD biosynthesis |
rnc | processing and degradation of RNA molecules |
rnjA | RNA processing |
rnpA | cleavage of precursor sequences from the 5 ends of pre-tRNAs |
rnpB | cleavage of precursor sequences from the 5 ends of pre-tRNAs |
rnz | processing of CCA-less tRNA precursors |
rodA | control of cell shape and elongation |
rplB | translation |
rplC | translation |
rplD | translation |
rplE | translation |
rplF | translation |
rplJ | translation |
rplL | translation |
rplM | translation |
rplN | translation |
rplP | translation |
rplQ | translation |
rplR | translation |
rplS | translation |
rplT | translation |
rplU | translation |
rplV | translation |
rplX | translation |
rpmA | translation |
rpmD | translation |
rpoA | transcription |
rpoB | [SW|transcription] |
rpoC | [SW|transcription] |
rpsB | translation |
rpsC | translation |
rpsD | translation |
rpsE | translation |
rpsG | translation |
rpsH | translation |
rpsI | translation |
rpsJ | translation |
rpsK | translation |
rpsL | translation |
rpsM | translation |
rpsN | translation |
rpsO | translation |
rpsP | translation |
rpsQ | translation |
rpsR | translation |
rpsS | translation |
scpA | segregation of replication origins |
scr | presecretory protein translocation |
secA | protein secretion |
secE | protein secretion |
secY | protein secretion |
serS | translation |
sigA | transcription |
sknR | control of prophage gene expression |
smc | segregation of replication origins |
spoVC | spore coat formation |
ssbA | [category|SW 3.1.1|DNA replication], [category|SW 3.1.5|DNA repair/ recombination] |
sufB | synthesis of iron-sulfur clusters |
sufC | synthesis of Fe-S clusters |
sufD | synthesis of Fe-S-clusters |
sufS | formation of iron-sulfur clusters in proteins |
sufU | transfer of sulfur from [protein|search|SufS ]to [protein|5991F051C5BAD61A0860BBC64A37DB9D16130998|SufB] |
sul | biosynthesis of folate |
tagA | biosynthesis of teichoic acid |
tagB | biosynthesis of teichoic acid |
tagD | biosynthesis of teichoic acid |
tagF | biosynthesis of teichoic acid |
tagG | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
tagH | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
tagO | biosynthesis of teichoic acid |
tilS | tRNA modification, control of [gene|4E7B9426CED372AA8A321A147116A3A589FBF20C|ftsH] expression |
tmk | TTP biosynthesis |
trmD | tRNA modification |
trmU | tRNA modification |
trpS | translation |
trxA | protection of proteins against oxidative damage |
trxB | keeps [protein|4E5C84FDC8FE2FEFF47306C91ECAB7F17D3E38E9|thioredoxin] in the reduced state |
tsaB | tRNA modification |
tsaD | tRNA modification |
tsf | translation |
tuaB | biosynthesis of teichuronic acid |
tufA | translation |
tyrS | translation |
uppS | cell wall biosynthesis |
valS | translation |
walK | control of cell wall metabolism |
walR | control of cell wall metabolism |
wapI | intercellular competition |
xre | regulation of [category|SW 5.1.1|PBSX prophage] gene expression |
ydiO | BsuM DNA modification |
ydiP | BsuM DNA modification |
yezG | inhibition of the cytotoxic activity of [protein|655C07294D3A04763049D6701A7296BB4AF8E6B9|YeeF] |
yhdL | control of [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM] activity |
ykuQ | biosynthesis of lysine and peptidoglycan |
ykuR | biosynthesis of lysine and peptidoglycan |
ylaN | unknown |
ylbI | lipopolysaccharide biosynthesis |
yloI | biosynthesis of coenzyme A |
yneF | unknown |
yphC | ribosome assembly |
yqcF | inhibition of the cytotoxic activity of [protein|D828A8E03C894D1082EFCB11BEF1384F04D17ECA|YqcG] |
yqeG | unknown |
yqfG | 16S rRNA maturation |
yrvO | tRNA modification |
ysxC | ribosome assembly |
ytaG | synthesis of coenzyme A |
yumC | redox reactions that involve ferredoxin and flavodoxin |
ywpB | fatty acid biosynthesis |
yxlC | control of [protein|801E92306971E26AD4AB155172B7F4EFDE2F9170|SigY] activity |
yxxD | inhibition of the cytotoxic activity of [protein|BD8C0563C7123B6DEC1EEB602BDF2C9D92D34991|YxiD] |
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